Dear All:

As some of you are aware, there is an FP7 Health call out in alternative 
testing methods due early February which will support two major projects 
of OpenTox relevance - one in computer modelling (PBPK, TTC, QSAR, 
pathways/mechanisms etc...) and one in data management and analysis. I 
will put my available effort into supporting the development of a 
proposal for the latter.

It would also be qood to see a good quality computer modelling proposal 
prepared which would build and extend on the OpenTox framework which 
could provide a very helpful foudation for such modelling area 
extensions.  If not done, I suspect significant resources will be wasted 
on inferior designed and less interoperable approaches.  I will be 
pleased to advise and support on such a proposal, but I will not have 
the capacity to lead it.

It is also good to see the move in expanding R&D in human-based 
cell/organ/systems biology approaches as replacement methods, which as 
with the ToxCast program, will drive new modelling requirements and 
innovation.

Barry