Dear Frits Daeyaert,

The OpenTox framework is designed as a network of webservices, which
can be deployed on the internet, but also on a local machine without
internet connection. Services can be accessed either through a REST API
or with Java and Ruby client libraries.

We (in silico toxicology) offer the lazar system for toxicity
predictions (see http://lazar.in-silico.ch), which is actively developed
both in terms of algorithms and models. lazar can run on a single
machine (although installation can be a little bit tricky - we offer
virtual appliances for that purpose). Let me know, if you need more
details.

I am sure other partners have similar services (IDEA e.g. has toxtree
http://toxtree.sourceforge.net/).

Best regards,
Christoph

On Tue, 24 Apr 2012 16:22:16 +0200, Micha Rautenberg <mr at mrautenberg.de> wrote:
> Fwd. this came via the opentox website's contact form.
> best, Micha
> 
> -------- Original-Nachricht --------
> Betreff: 	stand-alone programs for tox prediction
> Datum: 	Tue, 24 Apr 2012 14:52:37 +0200
> Von: 	frits at molmo.be
> An: 	www at opentox.org
> 
> 
> 
> You are receiving this mail because Frits Daeyaert
> frits at molmo.be
> is sending feedback about the site administered by you at http://www.opentox.org.
> The message sent was:
> 
> Dear sir, we are the developers of a de novo drug design algoritm 'synopsis' that designs compounds with desirable properties (a description can be found on www.molmo.be). We are exploring the possibility to extend synopsis with a toxicity prediction algorithm. For this we are looking for one or several stand-alone programs that take as input a single molecular structure and returns a score. Are there OpenTox applications available for this purpose? Kind regards Frits Daeyaert
> 
> 
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> Site Administrator
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