Endpoints
   Group Name
   1.Physicochemical effects 1.1.Melting point
   1.Physicochemical effects 1.2.Boiling point
   1.Physicochemical effects 1.3.Water solubility
   1.Physicochemical effects 1.4.Vapour pressure
   1.Physicochemical effects 1.5.Surface tension
   1.Physicochemical effects 1.6.Octanol-water partition coefficient
   (Kow)
   1.Physicochemical effects 1.7.Octanol-water distribution coefficient
   (D)
   1.Physicochemical effects 1.8.Octanol-air partition coefficient (Koa)
   1.Physicochemical effects 1.9.Air- water partition coefficient
   (Henry`s law constant, H)
   1.Physicochemical effects 1.10.Dissociation constant (pKa)
   2.Environmental fate parameters 1.Persistence: Abiotic degradation in
   water 2.1.a.Hydrolysis
   2.Environmental fate parameters 1.Persistence: Abiotic degradation in
   water 2.1.b.Oxidation
   2.Environmental fate parameters 1.Persistence: Abiotic degradation in
   water 2.1.c.Other
   2.Environmental fate parameters 2.Persistence: Abiotic degradation in
   air (Phototransformation) 2.2.a.Direct photolysis
   2.Environmental fate parameters 2.Persistence: Abiotic degradation in
   air (Phototransformation) 2.2.b.Indirect photolysis (OH-radical
   reaction, ozone-radical reaction, other)
   2.Environmental fate parameters 3.Persistence: Biodegradation
   2.3.a.Ready/not ready biodegradability
   2.Environmental fate parameters 3.Persistence: Biodegradation
   2.3.b.Biodegradation time frame (primary, ultimate degradation)
   2.Environmental fate parameters 4.Bioconcentration 2.4.a.BCF fish
   2.Environmental fate parameters 4.Bioconcentration 2.4.b.BCF other
   organisms
   2.Environmental fate parameters 5.Bioaccumulation 2.5.a.BAF fish
   2.Environmental fate parameters 5.Bioaccumulation 2.5.b.BAF other
   organisms
   2.Environmental fate parameters 2.6.Organic carbon-sorption partition
   coefficient (organic carbon; Koc)
   2.Environmental fate parameters 2.7.Adsorption/Desorption in soil
   2.Environmental fate parameters 2.8.Adsorption/Desorption in sediment
   2.Environmental fate parameters 2.9.Vegetation-water partition
   coefficient
   2.Environmental fate parameters 2.10.Vegetation-air partition
   coefficient
   2.Environmental fate parameters 2.11.Vegetation-soil partition
   coefficient
   3.Ecotoxic effects 3.1.Short-term toxicity to Daphnia (immobilisation)
   3.Ecotoxic effects 3.2.Short-term toxicity to algae (inhibition of the
   exponential growth rate)
   3.Ecotoxic effects 3.3.Acute toxicity to fish (lethality)
   3.Ecotoxic effects 3.4.Long-term toxicity to Daphnia (lethality,
   inhibition of reproduction)
   3.Ecotoxic effects 3.5.Long-term toxicity to fish (egg/sac fry, growth
   inhibition of juvenile fish, early life stage, full life cycle)
   3.Ecotoxic effects 3.6.Microbial inhibition (activated sludge
   respiration inhibition, inhibition of nitrification, other)
   3.Ecotoxic effects 3.7.Toxicity to soil microorganisms (inhibition of
   C-mineralisation, inhibition of N-mineralisation, other)
   3.Ecotoxic effects 3.8.Toxicity to earthworms (survival, growth,
   reproduction)
   3.Ecotoxic effects 3.9.Toxicity to plants (leaves, seed germination,
   root elongation)
   3.Ecotoxic effects 3.10.Toxicity to soil invertebrates (survival,
   growth, reproduction)
   3.Ecotoxic effects 3.11.Toxicity to sediment organisms (survival,
   growth, reproduction)
   3.Ecotoxic effects 12.Toxicity to birds 3.12.a.Short term toxicity
   (feeding, gavage, other)
   3.Ecotoxic effects 12.Toxicity to birds 3.12.b.Long-term toxicity
   (survival, growth, reproduction)
   4.Human health effects 4.1.Acute inhalation toicity
   4.Human health effects 4.2.Acute oral toxicity
   4.Human health effects 4.3.Acute dermal toxicity
   4.Human health effects 4.4.Skin irritation /corrosion
   4.Human health effects 4.5.Acute photoirritation
   4.Human health effects 4.6.Skin sensitisation
   4.Human health effects 4.7.Respiratory sensitisation
   4.Human health effects 4.8.Photosensitisation
   4.Human health effects 4.9.Eye irritation/corrosion
   4.Human health effects 4.10.Mutagenicity
   4.Human health effects 4.11.Photomutagenicity
   4.Human health effects 4.12.Carcinogenicity
   4.Human health effects 4.13.Photocarcinogenicity
   4.Human health effects 4.14.Repeated dose toxicity
   4.Human health effects 4.15.In vitro reproductive toxicity (e.g.
   embryotoxic effects in cell culture such as embryo stem cells)
   4.Human health effects 4.16.In vivo pre-natal-developmental toxicity
   4.Human health effects 4.17.In vivo pre-, peri-, post natal
   development and / or fertility (1 or 2 gen. Study or enhanced 1 gen
   study)
   4.Human health effects 18.Endocrine Activity 4.18.a.Receptor-binding
   (specify receptor)
   4.Human health effects 18.Endocrine Activity 4.18.b.Receptor binding
   and gene expression (specify receptor)
   4.Human health effects 18.Endocrine Activity 4.18.c.Other (e.g.
   inhibition of specific enzymes involved in hormone synthesis or
   regulation, specify enzyme(s) and hormone)
   5.Toxicokinetics 5.1.Skin penetration
   5.Toxicokinetics 5.2.Ocular membrane penetration
   5.Toxicokinetics 5.3.Gastrointestinal absorption
   5.Toxicokinetics 5.4.Blood-brain barrier penetration
   5.Toxicokinetics 5.5.Placental barrier penetration
   5.Toxicokinetics 5.6.Blood-testis barrier penetration
   5.Toxicokinetics 5.7.Blood-lung barrier penetration
   5.Toxicokinetics 5.8.Metabolism (including metabolic clearance)
   5.Toxicokinetics 5.9.Protein-binding
   5.Toxicokinetics 5.10.DNA-binding
   6.Other 6.6.Other
   QMRF Database [ http://nina.acad.bg:80/qmrf ] Report 2009-06-04 10:49